Fire officials said the estimated loss amounts to about $750,000.
Crews were called to the house in the 28200 block of Via Las Palmas shortly before 3 a.m. At that point, officials said flames had already burned up about 75 percent of the two-story, 8,500-square-foot house.
The structure was reportedly destroyed in about half an hour. No injuries were reported.
The cause of the blaze was under investigation.
City News Service contributed to this report.