For the 19th year, Walters got up close and personal with the people who have been front and center in the spotlight in 2011.
The lineup included the Kardashians, pop queen Katy Perry, stars of the hit series "Modern Family" and former GOP presidential nominee Herman Cain.
Barbara Walters Presents: The 10 Most Fascinating People of 2011
The star-studded list also included Simon Cowell, New York Yankee shortstop Derek Jeter and billionaire Donald Trump.
Walters' show highlights the year's top names in entertainment, pop culture and politics.
ABC News contributed to this report.