Spokesman Chris Goodman said Winehouse, who has publicly struggled with drug and alcohol abused, "is withdrawing from all scheduled performances" to focus on recovering.
"Everyone involved wishes to do everything they can to help her return to her best and she will be given as long as it takes for this to happen," he said.
The Grammy award winner was jeered and booed late Saturday as she performed in Serbia's capital Belgrade. She stumbled onto the stage, mumbled through her songs and sometimes wandered off.
The show was the first stop on her scheduled 12-stop European tour. Serbian media called the concert a "scandal," with the Blic daily labeling it "the worst in the history of Belgrade."
The next day, Winehouse's management canceled this week's shows in Istanbul and Athens. Her spokesman apologized to fans, saying Winehouse "feels that this is the right thing to do."
The 27-year-old British singer's appearances in Spain, Switzerland, Italy, Austria, Poland, Hungary and Romania have now also been scrapped. The tour had been due to end in Bucharest on Aug. 15.
Winehouse's music has been overshadowed by drug use, legal run-ins and a tempestuous marriage that ended in divorce. In 2008, she spent two weeks in a rehab clinic after the British tabloid, The Sun, released grainy footage showing Winehouse inhaling fumes from a pipe.
She recently went back to rehab to get ready for her tour. Last month, she spent a week in London's Priory clinic, which offers treatment for psychiatric problems, drug and alcohol addiction.
Winehouse shot to fame with her 2006 debut album "Back to Black," featuring her hit single "Rehab." There have long been plans for a follow up to the album, but new material has not been released.
The Associated Press contributed to this report.