Officials say John Jutiyasantayanon, 23, of Montclair fell 300 feet from a steep, sheer cliff near rocky terrain in the canyon just north of Altadena.
The Los Angeles County Sheriff's Department and the Altadena Mountain Rescue Team responded to reports of the fallen hiker at about 10:30 a.m., about a mile from the park entrance.
Authorities said Jutiyasantayano and his girlfriend veered off the recreational trail and attempted to go up a deer path that was less than a foot wide. Jutiyasantayano lost his footing and fell to the rocky bottom.
Officials said Jutiyasantayano's girlfriend tried to help him but got stuck. She suffered minor injuries and was taken to Huntington Memorial Hospital.
The trail head was shut down for investigation.
Two injured hikers became stranded in the same area Thursday and had to be rescued. This past Sunday, a young man fell 35 feet while scaling a cliff and died of his injuries.
Saturday's rescue was the 58th recovery effort this year at the canyon. Officials say more people are hiking because it's summer and are taking unnecessary risks.