Sheen said his so-called "Violent Torpedo of Truth" tour that followed his firing from the sitcom "Two and a Half Men" was an act of its own.
"I didn't really believe I had tiger blood or Adonis DNA. These were just jokes, you know," Sheen told Leno on the show Thursday.
Sheen also told Leno that CBS brass was right to fire him from the sitcom because he did occasionally show up for work not in the best of shape.
Sheen was dumped last March after the actor railed against his bosses, and they blasted him for his unpredictable behavior as a drug-abusing, reckless playboy.
"It was bad," Sheen said, "and I own my part in that, and I just want to make everything right."
He also told Leno he has not had any contact with his former castmates, but said he felt no animosity toward them.
Sheen also commented on his formerly strained relationship with his father, actor Martin Sheen, saying it's "totally repaired" and that they're "buddies again."
On Monday, the hit CBS comedy returns for a new season with Ashton Kutcher as Sheen's replacement.
Sheen praised Kutcher as being "accomplished," and when asked if he had any advice for his successor, he said he'd like to give him a hug and tell him, "Make me proud, dude."
The Associated Press contributed to this report.