Candace Parker scored 21 points in the win, which was part of an unmatched run for the Americans in the past 16 years. The U.S. has won 41 consecutive games in the Olympic competition since taking the bronze medal in 1992.
"It just shows the depth and talent in our country. Women's basketball, it's our sport - it's our sport," said Diana Taurasi, who has been a part of the last three gold medals. "We grew up playing since we were little and give it every single little bit of energy we have."
The U.S. women also struck gold in the 4x400-meter relay, beating out Russia and sprinting past third place Jamaica by over four seconds. Brigetta Barrett, 21, won the U.S. a silver medal for the high jump while also achieving a personal best.
The men didn't leave Saturday's competitions without snatching up medals for themselves. The U.S. took first place in the men's 10-meter platform dive. David Boudia beat out China's Bo Qui for the gold. Britain's Thomas Daley took the bronze after contesting his first attempt and improving his score from 75.60 points to 91.80.
But disappointment came as Brazil took home their second consecutive gold in women's volleyball, beating out the U.S. 3-1. It was the top-seeded Americans' only loss of the tournament. And legendary Jamaican sprinter Usain Bolt outran the U.S. men on the last leg of the 4-by-100 meters sprint relay. He took home the gold in world record time, leaving the silver for America.
The Associated Press and ABC News contributed to this report.