Sainte-Marie never minced words. Her 1964 debut album was called "It's My Way."
She was named "Billboard's" Best New Artist. Some of her songs addressed the mistreatment of Native Americans; she also wrote the powerful Vietnam protest song, "Universal Soldier."
"You know, a lot of people, they think that my career has been about either getting blacklisted because of 'Universal Soldier' or speaking out too strongly on behalf of Indigenous people," said Sainte-Marie. "I think I was seen as a loose cannon, saying too much, especially because there was so much Indian land being stolen at the time - so much! There was so much corruption going on. So I kind of got it. But here I am!"
Sainte-Marie was born on a Canadian reservation, adopted by an American couple and raised on the East Coast.
"They told me I couldn't be an Indian because there weren't any more around there. This was in Maine and Massachusetts where I was raised. So I was told I couldn't be a musician and I couldn't be an Indian and it just makes me laugh," said Sainte-Marie.
While many of Buffy's songs speak to adults, she loved speaking to children.
She appeared for years on "Sesame Street" and became a children's book author. One work involves her Cree heritage with a message to children about being themselves. Another from this longtime animal lover is a lullaby for pet adoption.
In 1983, Buffy became the first Indigenous person to win an Oscar. It was for co-writing "Up Where We Belong," the Best Original Song from "An Officer and a Gentleman."
"I still can't believe it. I think I just got lucky," said Sainte-Marie.