Crime scene investigators discovered blood covering a parked car following the violent stabbing attack in the 13500 block of Maie Avenue, authorities said.
Detectives also found a pool of blood on a sidewalk nearby.
The victim had been involved in a physical altercation with an unknown male, according to investigators. During the altercation, the victim suffered apparent stab wounds.
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They say the stabbing victim ran to a neighbor's house, pleading for help. Those neighbors called 911 and he was transported to a hospital.
The man later died at the hospital.
Deputies have not released a description of the suspect and the murder weapon remains outstanding.
The murder is being investigated as gang-related, the Sheriff's Department said.