The massive wildfire is so large, an image from NASA shows smoke that can be seen from space.
As of Monday, one structure has been lost and no injuries have been reported, according to Cal Fire officials.
The Alamo Fire began about 3:30 p.m. Thursday off Highway 166 near Twitchell Reservoir. The cause of the fire remains under investigation.
Fire crews from Los Angeles and Orange counties have joined the battle to fight the flames, where about 130 structures were threatened.
Mandatory evacuations were in place in the Tepusquet Canyon area from Blazing Saddle Drive to Santa Maria Mesa Road, White Rock Lane and Colson Canyon, Pine Canyon and Buckhorn Ridge. A total of 200 residents were affected.
An evacuation center was set at Minami Center, located at 600 W. Enos Street in Santa Maria.
A total of 14 wildfires were burning in the state, forcing nearly 8,000 evacuations in total. Firefighters were battling the fast-moving inferno from the air and the ground.
In Santa Barbara County, the Whittier Fire shut down both sides of a major highway and surrounded dozens of young campers and counselors at a nearby summer camp. The fire has charred more than 10,000 acres.