April 1, 1963 marked the first time viewers checked in with the show. Cast members past and present of the Emmy-winning drama toasted the milestone March 8 with cake and champagne.
The celebration allowed "General Hospital" veterans to reflect on the show's longevity.
"It means that the show has been entertaining people for two generations. It's a great honor to be on this show, and particularly at this time," said Anthony Geary, who plays Luke Spencer.
"This is it, we made it," said Genie Francis, who plays Laura. "Not only did we make it, we are coming back. Our ratings are up, we are strong. We're thrilled."
For the coming year, "General Hospital" will offer fans plenty of storyline surprises.
"General Hospital" airs weekdays at 1 p.m. on ABC7.