Authorities say the accident happened in the 900 block of North Wilmington Avenue at about 7 p.m. The driver fled from the scene and remains on the loose. A description of the suspect was not immediately available.
The women in the Lexus complained of pain and were taken to a local hospital. Their injuries do not appear to be serious, police said.
The building sustained serious damage and has been red-tagged.
Anyone with information is urged to call the L.A. County Sheriff's Department Compton Station at (310) 605-6500.