"I have a problem with alcohol, and the choices I have made while under the influence. I have struggled with this for some time," Ford said in statement.
This comes as reports surfaced about a second video showing the mayor smoking what appears to be crack cocaine.
The Globe and Mail newspaper says two of its reporters saw a new video from a self-professed drug dealer showing Ford apparently taking a drag from a crack pipe last weekend in his sister's basement. The paper reports that the dealer wants to sell the video for at least six figures.
Shortly after the newspaper asked the mayor for comment, his attorney announced his leave to seek treatment.
News reports of the existence of an earlier video of Ford apparently smoking crack first surfaced last May. After months of denial, he acknowledged that he smoked crack in a "drunken stupor" after police said they obtained a video that appears to show him smoking crack.
There are also reports of the mayor using shocking language at a bar this week. All this comes as the mayor fights for re-election. Many of his opponents are calling for his resignation, including John Tory, a rival candidate for his job.
The Associated Press contributed to this report.