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Agents with the Drug Enforcement Administration showed up at his Las Vegas home and office with a search warrant on Tuesday.
They combed through his clinic and a storage unit in Houston last week.
Drug Enforcement agents first arrived at Murray's home early Tuesday morning, searching the residence at Red Rock Country Club in the Summerlin community, west of the Vegas strip.
Then federal authorities also searched Murray's office just miles away, a virtual repeat of the raid performed on his Houston location last week.
The morning activity follows a report from the Associated Press that cites an unnamed law enforcement official who says Murray was the doctor that injected Jackson with the powerful drug propofol the night before he died.
As investigators focus on Murray, his attorney released a statement saying, "It's a waste of time responding to all these timed 'leaks' and 'anonymous' sources. I feel like a horse swatting flies. Everyone needs to take a breath and wait for these long delayed toxicology results."
ABC News has learned that those results, to be released this week, will show a potent drug cocktail, including oxycotin and demerol, found in Jackson's system. But that doesn't diminish Murray's possible role in the pop star's death. ABC News reports also say authorities may delay toxicology results until the criminal investigation is complete.
Murray left his private practice to work exclusively for /*Michael Jackson*/ last May. Murray was reportedly receiving $150,000 per month for his exclusive services.
"Unquestionably, there are other drugs involved here. But they don't have to prove this is the sole cause. They just have to prove this is a contributing cause. Not only that, since he is there on the scene, he should know what other drugs the patient is taking before administering a drug like this. So this doctor is in serious trouble," said defense attorney Roy Black.
The anonymous source cited by the AP says Jackson received propofol to sleep. The powerful anesthetic depresses breathing and lowers the heart rate, and is only supposed to be used within medical settings.
Toxicology reports are still pending, but investigators are working under the theory that the anesthetic propofol caused Jackson's heart to stop, a law enforcement official told The Associated Press on Monday. Jackson is believed to have been using the powerful drug for about two years, and investigators are trying to determine how many other doctors administered it, according to the official, who spoke on condition of anonymity because the investigation is ongoing.
The official said Jackson regularly received propofol and relied on it like an alarm clock. A doctor would administer it when Jackson went to sleep, then stop the IV drip when the singer wanted to wake up.
The day Jackson died, Murray gave him the drug through an IV sometime after midnight, the official said.
Investigators say Murray is cooperating and have not labeled him a suspect.
In addition to their probe of the Vegas-based doctor, they're also looking into how many other doctors provided Jackson with the drug.
On the financial front of Jackson's passing, his mother, Katherine, is asking a judge to force the administrators of her son's estate to give her more information. She is preparing for an upcoming hearing over who will receive permanent control of Michael's estate.
The Associated Press contributed to this story.
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