The retired animation artist drew composite sketches of the suspects for the police to use in the case.
The victim said a man conned his way into his house on the 2200 block of North Valley Street by saying he wanted money for roof work last Friday.
Once inside, a woman joined him, and they rummaged through his belongings and demanded cash before leaving.
No one was hurt in the incident.
The male suspect was described as white, 30 to 40 years old, 6 feet tall and 220 pounds. He had short black hair and was balding, with a beard and mustache. He was last seen wearing a black-and-white-striped sweatshirt and blue jeans.
The female suspect was described as a 30-year-old, 5 feet 1 inches, 120 pounds, with collar-length dirty-blonde hair. She had blue eyes and was last seen wearing a white V-neck shirt and blue jeans.
The suspects fled in a newer model white two-door sporty-looking hatchback with a chrome roof rack.
Anyone with information related to the incident was urged to call Burbank Police at (818) 238-3000.
