The winning numbers were 5, 16, 22, 23, 29 and Powerball of 6. One ticket was sold in Arizona and the other in Missouri.
Missouri officials said the winner bought the ticket at a Trex Mart store located at 17605 Highway Z in Dearborn. On Thursday, lottery officials verified the ticket that was presented to them and set a news conference for 11 a.m. CST Friday at North Platte High School, near where the ticket was bought.
In Arizona, the winning ticket was purchased at a 4 Sons Food Store at 13779 North Fountain Hills in Fountain Hills, but the winner has not yet come forward. Officials said it was a $10 Quick Pick ticket.
Americans went on a ticket-buying spree on Wednesday before the drawing. California is one of six states in the continental U.S. that doesn't play Powerball, but many people crossed into Arizona to get in on the drawing.
The jackpot, which had already rolled over 16 consecutive times without a winner, grew to $579.9 million by the time of the drawing, making the cash option $379.8 million. An additional 8.9 million players won smaller prizes.
The Associated Press contributed to this report.