Heigl's comments in the past have been known to make waves in the entertainment world.
In 2007, she called "Knocked Up," in which she starred, "a little sexist." Later, she refused to seek an Emmy nomination after saying "Grey's" writers didn't give her enough award-worthy material.
Heigl's latest dramedy, "Life as We Know It,"opens nationwide next week.
The Associated Press contributed to this report.