A TV ad declaration made by U.S. Senate candidate Christine O'Donnell of Delaware tops this year's list.
In the ad, she said, "I'm not a witch."
O'Donnell was responding to reports she had dabbled in witchcraft.
That quote tied for first place with the infamous line uttered by BP's CEO Tony Hayward to reporters after the worst offshore oil spill in U.S. history.
Hayward said, "I'd like my life back," which led to outrage as the people of the Gulf Coast struggled to protect their livelihoods.
O'Donnell also made the list for questioning, during a debate in October, whether the First Amendment includes the language "separation of church and state."
The original Yale Book of Quotations was published in 2006.
Here's the list:
No 1: (Tie) "I'm not a witch." Christine O'Donnell, TV advertisement, Oct. 4.
No 1: (Tie) "I'd like my life back." Tony Hayward, comment to reporters, May 30.
No. 3: "If you touch my junk, I'm gonna have you arrested." airline passenger John Tyner, remark to Transportation Security Administration worker at San Diego airport, Nov. 13, 2010
No. 4: "Don't retreat. Instead - reload!" Sarah Palin, tweet, March 23.
No. 5: "Chi! Chi! Chi! Le! Le! Le! Los mineros de Chile!" Chant at Chilean mine rescue, Oct. 13.
No. 6: "I hope that's not where we're going, but you know, if this Congress keeps going the way it is, people are really looking toward those Second Amendment remedies. They're saying: My goodness, what can we do to turn this country around?" Sharron Angle, radio interview in January.
No. 7: "We have to pass the (health care) bill so you can find out what is in it." Nancy Pelosi, speech to National Association of Counties, March 9.
No. 8: "I'm going to take my talents to South Beach." LeBron James, TV broadcast, July 8.
No. 9: "You're telling me that the separation of church and state is found in the First Amendment?" Christine O'Donnell, Delaware senatorial debate, Oct. 19.
No. 10: "They should never have put me with that woman. ... She was just a sort of bigoted woman who said she used to be Labour." Gordon Brown, comments about a voter he met while campaigning for British general election, Apr. 28.
The Associated Press contributed to this report.