Investigators said Alicia Carolina Benites of Tarzana showed up to the LAPD's West Valley Community Police Station about 10 a.m. Sunday.
The incident happened at the intersection of Saticoy Street and Atoll Avenue at around 1:40 a.m.
A pedestrian was crossing the street when he was struck by a vehicle. He was pronounced dead at the scene.
Witnesses said the driver plowed into the victim and sped away, leaving the man to die. Police said the driver headed westbound on Saticoy Street.
Authorities said the woman's car was accurately described by witnesses as a four-door, white sedan with some front-end damage.
She was booked for felony hit-and-run and is being held on $50,000 bail.