The cat was spotted shortly before noon near a concrete column of the Van Buren Boulevard bridge.
Motorists had been calling the Riverside County Animal Services Department since Thursday regarding the cat, but responding officers had no luck finding her.
That's until Thursday when animal control officers Tiffany Fuller, Jenny Selter and Craig Wellmerling spotted her.
Selter plucked the kitty while holding a net in case the cat decided to bold, according to animal services spokesman John Welsh.
"We have no idea how she got there," said Fuller.
The 3-year-old domestic short-haired cat was later named "Vanity," and treated for dehydration.
CNS contributed to this report.