Eyewitnesses told police they saw a black Ford Mustang and a silver Mercedes-Benz racing each other moments before the crash just before 2 p.m. on San Vicente near Burnside Avenue.
The driver of the Mustang apparently went up onto the median dividing San Vicente and took out a couple of small trees before flipping over. The driver was taken to a hospital with non-life-threatening injuries.
The second driver fled the scene.
"The car blew and he hit the tree, then he rolled three or four times, taking out another tree in the median and stopped when he hit another car," said witness Melody Cervantes.
Police said a nitrous tank was missing from the vehicle.
Both sides of San Vicente Boulevard were closed during the investigation.
Some residents said street racing has recently become a problem on their street.
"These guys are going in excess speeds of 70-80 mph, and these cars are souped up. All of a sudden you just hear a pop and then the engines start screaming," said reside George Zaldumbide.
Resident said they have complained repeatedly to the Los Angeles Police Department about the street racing and fear one day innocent lives may be lost.
"I've called the police numerous times, I talked to the people from my neighborhood association, who talked to our lead officer, and something was suppose to be done, but nothing's ever happened," said resident Ken Rogers. "All my neighbors are really upset about it and we're just waiting for someone to get hurt."