There are an estimated 1,000 pot shops in the metropolitan area.
The group called "Americans for Safe Access" is upset with a provision in the ordinance which seeks to reduce the number of outlets to only 70.
The new ordinance will take effect Marth 14, 2010.
The ordinance requires dispensaries be at least 1,000 feet away from sensitive areas including schools, public parks, public libraries, religious institutions, child care facilities, youth centers, rehab centers, and other dispensaries.
Marijuana advocates call the new regulations unreasonable and impractical.
City News Service and the Associated Press contributed to this report.
