"Lady Gaga and the Muppets' Holiday Spectacular" will air on the network Thanksgiving at 9:30 p.m. ET. The 90-minute special will also feature Sir Elton John, Joseph Gordon-Levitt, and RuPaul.
According to ABC, the special will include a duet by Lady Gaga and Kermit the Frog. Also, viewers will get a sneak peek at the Muppets' upcoming movie, which is set to hit theaters March 2014. "Muppets Most Wanted" features a cameo by Gaga, who has a long history with the Muppets.
Kermit the frog was the pop icon's date to the 2009 MTV Video Music Awards, much to the consternation of Miss Piggy.
In a statement released by ABC, Gaga tried to ease Miss Piggy's worries.
"Can't wait to see the gang again and I hope Miss Piggy's still not mad about Kermit. We're just friends!" she said.
In the Thanksgiving night special, Lady Gaga will perform songs from her new album ARTPOP, which is set to debut Nov. 11. This will be Gaga's second primetime Thanksgiving night special for ABC.