A number of cars were also involved in the accident.
Three westbound lanes were closed for a couple hours while crews cleaned up the mess.
Two people were injured and taken to local hospitals.
2 injured after semi overturns on the 101
TARZANA (KABC) The accident occurred at about 6 a.m. near the Winnetka Avenue onramp, backing up traffic to the 405 Freeway interchange.
