The 50-year-old artist is best known for the songs "Come to My Window" and "I'm the Only One."
She was joined by her children and her mother on the special day as she received the 2,450th sidewalk star in Hollywood on Tuesday.
Etheridge's star is in front of the Hard Rock Cafe Hollywood.
The ceremony also served to launch the Pinktober campaign, a series of concerts and events that will raise money and breast cancer awareness. Etheridge, who was diagnosed with breast cancer in 2004, has been an artist ambassador for Pinktober for six years.
The Associated Press contributed to this report.