Highlights included Lady Gaga's emotional performance, Brendan Fraser's moving win and host Jimmy Kimmel's jokes on 'the slap.'
LOS ANGELES -- "Everything Everywhere All At Once" lived up to its title Sunday night at the Oscars, with the film taking home gold in seven out of 11 nominated categories, including best picture and best director, along with three acting nods.
The eccentric tale about a Chinese immigrant family and alternate realities, from directing duo Daniel Kwan and Daniel Scheinert, is the first-ever science fiction film to win the top prize.
"Everything Everywhere" star Michelle Yeoh made history as the first Asian woman to win best actress, while co-stars Ke Huy Quan and Jamie Lee Curtis also won in the supporting actor and actress categories, respectively. Only two other films in Oscar history -- "A Streetcar Named Desire" and "Network" -- have won three acting Oscars.
"Thank you for all the little boys and girls who look like me tonight," Yeoh said during her acceptance speech. "This is proof that dreams do come true. And ladies, don't let anyone ever tell you you're past your prime."
Curtis paid homage to her Oscar-nominated parents, Janet Leigh and Tony Curtis, after her win. It comes more than 60 years after her mother was nominated for her supporting acting work in "Psycho." Her father received a nod in 1959 in the best actor category for "The Defiant Ones."
"My mother and my father were both nominated for Oscars in different categories," Curtis said, beginning to cry as she accepted the award. "I just won an Oscar!"
Brendan Fraser, the once ubiquitous '90s star, took the stage to an overwhelming ovation as he won the award for best actor for his role in "The Whale."
Former child star Quan's win was also met with a standing ovation, capping his own extraordinary comeback.
"They say stories like this only happen in the movies. I can't believe it's happening," he said. "This is the American dream."
The film with the next highest number of wins was German-language WWI epic "All Quiet on the Western Front," with four.
Adding to the night of emotional moments was Lady Gaga, who took to the stage to perform "Hold My Hand," her Oscar-nominated original song from "Top Gun: Maverick." She stunned audiences with a costume change, in which she shed her runway gown and makeup for a black graphic tee, ripped jeans and some Chucks.
"We want you to have fun, feel safe, and most importantly, we want me to feel safe," Kimmel said, referring to the moment Will Smith smacked presenter Chris Rock, and went on to win best actor. "So, we have strict policies in place. If anyone in this theater commits an act of violence at any point during the show, you will be awarded the Oscar for best actor and permitted to give a 19-minute long speech."
WATCH: Kimmel's opening monologue
(Not listed in order of presentation)