The site's editor-in-chief, Matt Atchity said "Toy Story 3" collected positive reviews from 99 percent of critics, making it the best-reviewed film in wide release of 2010.
The animated toy flick beat out the Facebook saga, "The Social Network," which got a positive review score of 97 percent.
Other Golden Tomato winners announced Tuesday include the rebooted Western "True Grit," the Banksy documentary "Exit Through the Gift Shop" and "Last Train Home," a documentary about Chinese migrant workers.
The Associated Press contributed to this report.