It's been nearly three weeks since Lisa's disappearance from her parents' home in Kansas City.
According to ABC News, at least three witnesses say they saw the same thing in the early hours of Oct. 4 - a man walking with a baby who didn't have a coat on about a block from the house.
Police were initially skeptical of the report and interviewed one of the witnesses four times. Capt. Steve Young, a police spokesman, said authorities have cleared nearly 700 tips and leads. They are now pursuing 65 tips and leads in several states.
Investigators appeared to have turned their attention this week to the parents of the child, Deborah Bradley and Jeremy Irwin, and they scoured the home again.
According to a police affidavit released Friday, an FBI cadaver dog reacted to the scent of a dead person inside the house. The affidavit said the dog taken into the house Monday indicated a "hit" on the floor of Bradley's bedroom.
The parents have said they believe a stranger took Lisa from her crib in the middle of the night.
ABC News and the Associated Press contributed to this report.