"Hosting this banner event for the global technology community is a major win for Los Angeles and an important boost for our local economy," Villaraigosa said.
The event is expected to draw up to 15,000 people to the downtown area.
Microsoft CEO Steve Ballmer said Los Angeles is a dynamic, exciting city that inspires creativity and innovation.
"It's an ideal setting for our global community of 15,000 partners from 120 countries to share their ideas and energy for technology and business opportunities in the years ahead," he said.
The conference will be held July 10 -14, 2011.