The drive is seven-days long and runs through Monday at Children's Hospital Los Angeles.
Similar drives during the first three rounds of the playoffs drew 121 donors, helping nearly 350 children.
Platelet donations are needed for children undergoing chemotherapy or radiation treatment and those who have had a bone marrow transplant.
Donors will get a chance to win tickets to Game 3 of the Stanley Cup Finals. One lucky donor will receive a hockey puck signed by Kings captain Dustin Brown.
To donate, you need to make an appointment by calling (323) 361-2441 or emailing blooddonorcenterchla.usc.edu. Appointments are available at 7:30 a.m., 8 a.m., 10 a.m., 10:30 a.m. 12:30 p.m., 1 p.m. and 3 p.m. daily throughout the drive. Donating takes two hours. Additional information is available on the Kings' website.
People who have taken aspirin or other anti-inflammatory drugs in the previous 48 hours are not allowed to donate.
The Kings take on the New Jersey Kings in Game 1 on Wednesday at 5 p.m. PT.